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Anti-angiogenesis approach to fight cancer
In what has been termed as the
"fourth arm" of cancer treatment, (chemotherapy, radiation therapy
and surgery are numbers one, two and three) angiogenesis inhibitors have been
hailed as a significant advance in the long fight against cancer. Instead of
aiming their firepower at tumours themselves, anti-angiogenic inhibitors do
not have the harsh side effects of conventional cancer treatment.
CNN reported recently that cancer
needs a growing network of blood vessels to survive. Shutting down this
process called angiogenesis should arrest tumours or even destroy them.
Recent clinical trials of an experimental drug, conducted at Duke University,
confirmed that cutting off a tumor's blood supply could improve cancer
survival.
Researchers at Ohio State University
Medical Center (Columbus, Ohio), University of Kuopio (Kuopio, Finland), and
Creighton University Medical Center (Omaha, Nebraska) have shown that Optivin
significantly inhibits angiogenesis both in vitro and in vivo, thus offering
potential benefit in the treatment of related disorders such as cancer and
inflammation.
"For the past 50 years, almost
all cancer therapy has been aimed at the cancer cell. But this cell can
quickly become drug-resistant and conventional therapy has harsh side
effects. Unlike chemotherapy, angiogenic inhibitors will be used on a
long-term basis because they are non-toxic and do not generate drug
resistance."
Dr. Judah Folkman
World-renowned Harvard surgeon,
Founding father of Angiogenesis
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What
Experts Say
“It's hard to go
wrong if you fortify your diet with colorful foods. Almost every one of
them is loaded with disease-proofing compounds.
The
Color Code
James A Joseph, Ph.D., Daniel A. Nadeau, M.D., and Anne
Underwood
"Fruits and vegetables with
the deepest colors generally are most beneficial because they contain
high levels of antioxidants."
Jean
Carpenter
Author of bestseller
"Stop Aging Now"
"Rats injected with cancer causing
agents and then fed a berry-rich diet had 80 per cent fewer malignant
tumours compared to those without berries in their diet."
Gary
Stoner, Ph.D, Biologist
Ohio State University
In light of the
increasing antibiotic resistance of many bacteria, the public health
significance of the role of foods, such as cranberry, in preventing
infections warrants further consideration. A lower number of infections
means reduced use of antibiotics and lower potential risk of developing
further bacterial antibiotic resistance."
Betsy Foxman, Professor of
Epidemiology and director at the Center for Molecular and Clinical
Epidemiology, University of Michigan School of Public Health
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"Older animals with
impairments in learning, memory and coordination begin to show
significant signs of improvement after a 2-month diet of blueberries.
Anthocyanins found in the fruit appears to have triggered the birth of
new neurons - an act called neurogenesis - making the brain look and
act like a younger one."
Barbara
Shukitt-Hale, Ph.D.
USDA Scientist,
Neuroscience Laboratory
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